Neuropathy No More By JODI KNAPP Neuropathy No More is an eBook which is a compilation of all the essential information and details about the nervous system and how to keep it active and healthy. With the help of this program, one can get a relief from the symptoms of neuropathy. This eBook not only tells you about the nervous system, but also helps to provide essential information to get relief from the condition of neuropathy. It also provides information about how you can prevent this condition from coming back in the near future.
What is diabetic neuropathy?
Diabetic neuropathy is a type of nerve damage that occurs as a complication of diabetes. It happens when consistently high blood sugar levels injure nerves throughout the body, most commonly affecting the legs and feet.
What is Diabetic Neuropathy?
It results from chronic high blood glucose damaging nerves and their blood supply.
Can affect sensory nerves (feeling), motor nerves (movement), and autonomic nerves (involuntary functions).
One of the most common long-term complications of both type 1 and type 2 diabetes.
Types of Diabetic Neuropathy
Type Description Common Symptoms
Peripheral neuropathy Most common type; affects feet and hands Numbness, tingling, burning pain, loss of sensation
Autonomic neuropathy Affects involuntary body functions Digestive issues, bladder problems, blood pressure changes, sexual dysfunction
Proximal neuropathy Affects thighs, hips, or buttocks Muscle weakness, pain, difficulty standing or walking
Focal neuropathy Sudden weakness or pain in a specific nerve or group Double vision, facial paralysis, chest or abdominal pain
Symptoms
Numbness, tingling, burning, or sharp pain in feet and hands
Loss of sensation increasing risk of injuries
Muscle weakness or cramps
Digestive problems, urinary issues, or heart rate abnormalities (if autonomic nerves affected)
Importance of Management
Maintaining good blood sugar control is key to preventing or slowing progression.
Treatments focus on symptom relief and improving quality of life.
Would you like to learn about diagnosis, treatment, or prevention of diabetic neuropathy?
Chemotherapy-Induced Peripheral Neuropathy (CIPN) is nerve damage caused by certain chemotherapy drugs used in cancer treatment. It affects the peripheral nerves, especially those in the hands and feet, leading to sensory, motor, and sometimes autonomic symptoms.
What is CIPN?
Definition: A common side effect of some chemotherapy agents that results in nerve injury.
Nerves affected: Primarily sensory nerves, but motor and autonomic nerves can also be involved.
Symptoms: Tingling, numbness, burning pain, weakness, and balance problems, usually starting in a “glove and stocking” pattern (hands and feet).
Common Chemotherapy Drugs Associated with CIPN
Drug Class Examples Typical Neuropathy Features
Platinum compounds Cisplatin, Carboplatin Sensory neuropathy, numbness, pain
Taxanes Paclitaxel, Docetaxel Sensory and motor symptoms
Vinca alkaloids Vincristine, Vinblastine Motor neuropathy, weakness
Proteasome inhibitors Bortezomib Sensory and autonomic neuropathy
Thalidomide Thalidomide, Lenalidomide Sensory neuropathy, pain
Mechanism
Chemotherapy drugs damage nerve fibers (axons or myelin sheath) or the dorsal root ganglia.
Leads to impaired nerve signaling.
Impact on Patients
Can limit chemotherapy dosing or cause treatment delays.
May persist after treatment ends.
Significantly affects quality of life.
Management
Dose adjustments or switching drugs.
Symptomatic treatment with medications like gabapentin or duloxetine.
Physical therapy and supportive care.
If you want, I can provide more details on symptom management or prevention strategies for CIPN!
Neuropathy No More By JODI KNAPP Neuropathy No More is an eBook which is a compilation of all the essential information and details about the nervous system and how to keep it active and healthy. With the help of this program, one can get a relief from the symptoms of neuropathy. This eBook not only tells you about the nervous system, but also helps to provide essential information to get relief from the condition of neuropathy. It also provides information about how you can prevent this condition from coming back in the near future.