What are the risk factors for developing neuropathy?

October 21, 2024


Neuropathy No More By JODI KNAPP Neuropathy No More is an eBook which is a compilation of all the essential information and details about the nervous system and how to keep it active and healthy. With the help of this program, one can get a relief from the symptoms of neuropathy. This eBook not only tells you about the nervous system, but also helps to provide essential information to get relief from the condition of neuropathy. It also provides information about how you can prevent this condition from coming back in the near future.


What are the risk factors for developing neuropathy?

Several risk factors can increase the likelihood of developing neuropathy, particularly peripheral neuropathy. These risk factors vary based on the type and underlying causes of neuropathy but generally include the following:

1. Diabetes

  • Most common risk factor: Diabetic neuropathy affects around 50% of people with diabetes, especially those with poorly controlled blood sugar levels.
  • Duration of diabetes: The longer someone has diabetes, the greater the risk of developing neuropathy.

2. Chronic Alcohol Use

  • Alcoholic neuropathy: Chronic excessive alcohol consumption can lead to nerve damage due to poor nutrition, especially vitamin deficiencies like B12, B6, and thiamine (B1).
  • Toxic effect of alcohol: Direct nerve damage from alcohol over time.

3. Vitamin Deficiencies

  • B Vitamins (especially B12): A deficiency in key nutrients, particularly B12, B6, and folate, is associated with peripheral nerve damage.
  • Malabsorption issues: Conditions like celiac disease, Crohn’s disease, or gastric surgery can lead to poor nutrient absorption, increasing neuropathy risk.

4. Infections

  • Viral and bacterial infections: Conditions like HIV/AIDS, Lyme disease, and Hepatitis B and C are linked to neuropathy.
  • Post-infectious: Some people may develop neuropathy after recovering from viral infections.

5. Chemotherapy and Other Toxic Exposures

  • Chemotherapy drugs: Certain cancer treatments (e.g., cisplatin, vincristine) are associated with chemotherapy-induced peripheral neuropathy (CIPN).
  • Toxins: Exposure to heavy metals (lead, mercury) or industrial chemicals can also lead to neuropathy.

6. Autoimmune Diseases

  • Conditions like lupus, rheumatoid arthritis, or Guillain-Barré syndrome: The immune system attacking the nerves can cause neuropathy.
  • Chronic inflammation: Persistent inflammation in autoimmune diseases can damage nerves.

7. Chronic Kidney Disease (Uremia)

  • Uremic neuropathy: Poorly functioning kidneys can lead to toxin buildup in the blood, causing nerve damage.
  • End-stage renal disease: People undergoing dialysis may develop neuropathy.

8. Injury or Trauma

  • Nerve compression: Physical injuries or repetitive stress, like carpal tunnel syndrome or injuries from accidents, can lead to localized neuropathy.
  • Fractures or surgical interventions: Nerves may be damaged during trauma or surgery.

9. Genetics

  • Inherited conditions: Some forms of neuropathy, such as Charcot-Marie-Tooth disease, are hereditary and may manifest early in life.
  • Family history: Having a family member with neuropathy can increase the risk of inherited neuropathies.

10. Medications

  • Certain drugs: In addition to chemotherapy, other medications like certain antibiotics, antiretrovirals (for HIV), or anticonvulsants can lead to neuropathy.

11. Smoking

  • Vascular damage: Smoking impairs circulation, which can lead to reduced blood flow to peripheral nerves, increasing the risk of neuropathy.

12. Age

  • Older age: The risk of neuropathy increases with age, particularly due to conditions like diabetes, vascular disease, and nutritional deficiencies, which become more common.

13. Obesity

  • Metabolic syndrome: Being overweight or obese increases the risk of diabetes and, consequently, diabetic neuropathy.
  • Inflammation: Obesity is associated with low-grade chronic inflammation, which can damage nerves over time.

14. Excessive Pressure on Nerves

  • Repetitive stress or long periods of compression: Certain occupations or activities that cause prolonged pressure on nerves (e.g., sitting or standing in awkward positions for long periods) can lead to nerve damage.

By managing these risk factors—particularly controlling blood sugar levels, avoiding excessive alcohol, maintaining good nutrition, and preventing injuries—many people can reduce their risk of developing neuropathy.


Neuropathy No More By JODI KNAPP Neuropathy No More is an eBook which is a compilation of all the essential information and details about the nervous system and how to keep it active and healthy. With the help of this program, one can get a relief from the symptoms of neuropathy. This eBook not only tells you about the nervous system, but also helps to provide essential information to get relief from the condition of neuropathy. It also provides information about how you can prevent this condition from coming back in the near future.