Can neuropathy cause muscle weakness?

January 16, 2025


Neuropathy No More By JODI KNAPP Neuropathy No More is an eBook which is a compilation of all the essential information and details about the nervous system and how to keep it active and healthy. With the help of this program, one can get a relief from the symptoms of neuropathy. This eBook not only tells you about the nervous system, but also helps to provide essential information to get relief from the condition of neuropathy. It also provides information about how you can prevent this condition from coming back in the near future.


Can neuropathy cause muscle weakness?

Yes, neuropathy can cause muscle weakness. This happens when the motor nerves, which are responsible for sending signals from the brain and spinal cord to muscles, become damaged. The effects of this damage can vary depending on the type of neuropathy and the specific nerves involved, but muscle weakness is a common symptom. Here’s how neuropathy contributes to muscle weakness:

1. Motor Nerve Damage

  • Impaired Signal Transmission: Motor nerves transmit electrical signals from the central nervous system to muscles to initiate movement. When these nerves are damaged by neuropathy, they may not be able to effectively transmit signals to the muscles. As a result, the muscles may become weaker because they are not receiving the necessary stimulation to function properly.
  • Progressive Muscle Atrophy: Over time, muscles that are not being properly activated can begin to shrink (atrophy) due to lack of use and stimulation. This can further exacerbate muscle weakness.

2. Reduced Muscle Strength

  • Weakness in Specific Muscle Groups: Depending on the type of neuropathy, muscle weakness can affect specific areas of the body. For example, in diabetic neuropathy, which often affects the legs and feet, individuals may experience weakness in the lower limbs, making walking difficult. In peripheral neuropathy, the arms and hands may also be affected, leading to difficulty with fine motor tasks like gripping objects or writing.
  • Loss of Coordination: In addition to muscle weakness, neuropathy can also impair coordination, making it harder to perform tasks that require precise movements, even if muscle strength is intact.

3. Involvement of Specific Nerves

  • Axonal Degeneration: In some types of neuropathy, the axons (the long projections of nerve cells that transmit electrical signals) become damaged. This can lead to significant loss of muscle strength and control because the muscle fibers no longer receive effective input from the nervous system.
  • Demyelination: In conditions like Guillain-Barré Syndrome or chronic inflammatory demyelinating polyneuropathy (CIDP), the myelin sheath (the protective covering around nerves) becomes damaged, leading to delayed or blocked nerve signals. This can cause both weakness and pain, particularly in the arms, legs, and torso.

4. Impact on Reflexes and Muscle Function

  • Reduced Reflexes: Neuropathy can affect the reflex pathways, reducing the speed and efficiency of reflex responses. This can lead to weakness because the body’s natural protective responses, such as quickly adjusting posture or balance, are slowed down.
  • Fatigue: Muscle weakness caused by neuropathy can make it harder to perform everyday activities, leading to increased fatigue. As muscles become weaker, they require more effort to perform basic tasks.

Managing Muscle Weakness from Neuropathy

  • Physical Therapy: Strengthening exercises and physical therapy can help maintain muscle strength and function, improving overall mobility and reducing the risk of falls.
  • Medications: Certain medications, such as pain relievers or medications aimed at improving nerve function, may be prescribed to help manage the symptoms of neuropathy and reduce muscle weakness.
  • Assistive Devices: Depending on the severity of the muscle weakness, mobility aids like walkers or canes may be needed to assist with balance and walking.

In conclusion, muscle weakness is a common and significant symptom of neuropathy. The extent of the weakness depends on the type of neuropathy, the nerves affected, and how much damage has occurred.


Neuropathy No More By JODI KNAPP Neuropathy No More is an eBook which is a compilation of all the essential information and details about the nervous system and how to keep it active and healthy. With the help of this program, one can get a relief from the symptoms of neuropathy. This eBook not only tells you about the nervous system, but also helps to provide essential information to get relief from the condition of neuropathy. It also provides information about how you can prevent this condition from coming back in the near future.