What is peripheral neuropathy?

May 14, 2025


Neuropathy No More By JODI KNAPP Neuropathy No More is an eBook which is a compilation of all the essential information and details about the nervous system and how to keep it active and healthy. With the help of this program, one can get a relief from the symptoms of neuropathy. This eBook not only tells you about the nervous system, but also helps to provide essential information to get relief from the condition of neuropathy. It also provides information about how you can prevent this condition from coming back in the near future.


What is peripheral neuropathy?

Peripheral neuropathy occurs when peripheral nerves—the nerves outside the brain and spinal cord—are damaged. Because these nerves control movement, sensation, and autonomic functions (like blood pressure or digestion), when they are damaged, the symptoms can be very varied, depending on the nerves affected.

???? Primary Characteristics of Peripheral Neuropathy
???? What it affects:
Sensory nerves → Sensations like pain, temperature, touch, and position

Motor nerves → Muscle control and movement

Autonomic nerves → Involuntary actions like heart rate, sweating, digestion

⚠️ Common Symptoms
Symptoms usually start in hands or feet and may spread upward:

Numbness or tingling (“pins and needles”)

Burning or shooting pain

Muscle weakness

Loss of coordination or balance

Sensitivity to touch (even light touch may hurt)

Changes in skin, hair, or nails

Low blood pressure or digestive problems (if autonomic nerves are affected)

???? Common Causes
Diabetes (most common cause)

Vitamin B12 or other deficiency

Alcohol abuse

Infections (e.g., shingles, Lyme disease)

Autoimmune disorders

Medications (e.g., chemotherapy)

Repetitive injuries (e.g., carpal tunnel syndrome)

Toxins or heavy metals

???? Diagnosis
Medical history + physical exam

Blood tests (e.g., for diabetes, vitamin levels)

Nerve conduction studies or EMG

Skin or nerve biopsy (in some rare instances)

???? Treatment Goals
Peripheral neuropathy can’t always be cured, but treatment aims at:

Managing the underlying cause (such as controlling blood sugar)

Relieving symptoms (pain medications, physical therapy, etc.)

Preventing further nerve damage

Consider the following analogy:
Peripheral neuropathy is like a frayed wire—when the wiring or insulation within a nerve is injured, the messages get scrambled or cut off altogether.

Tell me if you would like information on a specific cause like diabetes or autoimmune disease.

Autonomic neuropathy is a type of nerve damage that happens in the autonomic nervous system (ANS)—the system that controls involuntary body functions such as heart rate, blood pressure, digestion, temperature regulation, bladder function, and sexual response.

???? What Does the Autonomic Nervous System Do?
The ANS makes your body work automatically. It controls:

Heartbeat and blood pressure

Breathing rate

Sweating

Digestion and bowel movements

Bladder function

Pupil enlargement and constriction

Sexual arousal and performance

⚠️ What Happens in Autonomic Neuropathy?
When the ANS is damaged, these involuntary functions become disorganized or interrupted, causing diverse symptoms:

✅ Common Symptoms by System:
System Affected Symptoms
Cardiovascular Dizziness, fainting, rapid or irregular heartbeat, low BP
Digestive Bloating, nausea, vomiting, constipation, diarrhea
Urinary Incontinence, inability to initiate urination, frequent UTIs
Sweat Glands Excessive sweating (particularly at night) or lack of sweating
Sexual Function Erectile dysfunction in men, vaginal dryness in women
Pupils/Eyes Sensitivity to light, slow pupil reaction
Thermal Regulation Intolerance to heat due to impaired sweating

???? Autonomic Neuropathy Causes
Diabetes (most common)

Autoimmune disorders (e.g., lupus, Sjögren’s syndrome)

Parkinson’s disease

Alcoholism

Chemotherapy or radiation

Amyloidosis

Certain infections (e.g., HIV)

Inherited neurological diseases (e.g., familial dysautonomia)

???? Diagnosis
Blood pressure measurements (especially with a change in position)

ECG or heart rate variability tests

Gastric emptying tests

Sweat tests

Bladder function studies

???? Treatment and Management
There is no cure for autonomic neuropathy, but the symptoms can usually be managed:

Medication (for GI motility, blood pressure control, etc.)

Dietary modification (small, frequent meals; fluids and salt supplements)

Compression stockings (to prevent pooling of blood in the legs)

Bladder training and pelvic therapy

Blood sugar control (crucial for diabetics)

Would you like to know how autonomic neuropathy differs from peripheral neuropathy, or how specific symptoms (e.g., digestive or cardiovascular) can be controlled?


Neuropathy No More By JODI KNAPP Neuropathy No More is an eBook which is a compilation of all the essential information and details about the nervous system and how to keep it active and healthy. With the help of this program, one can get a relief from the symptoms of neuropathy. This eBook not only tells you about the nervous system, but also helps to provide essential information to get relief from the condition of neuropathy. It also provides information about how you can prevent this condition from coming back in the near future.