How does Parkinson’s disease affect vision?

May 29, 2024

How does Parkinson’s disease affect vision?

Parkinson’s disease (PD) can significantly affect vision and various aspects of visual processing. These visual disturbances can result from both the disease itself and the side effects of medications used to treat PD. Here’s how Parkinson’s disease can impact vision:

1. Blurred Vision

Causes:

  • Medications: Anticholinergic medications used to treat PD can reduce tear production, leading to dry eyes and blurred vision.
  • Autonomic Dysfunction: PD can cause reduced blinking, leading to dry eyes and subsequent blurred vision.

Management:

  • Artificial Tears: Use of lubricating eye drops to alleviate dryness.
  • Regular Eye Exams: Routine check-ups with an ophthalmologist to monitor and manage changes in vision.

2. Difficulty with Eye Movements

a. Saccades and Smooth Pursuit:

  • Description: Saccades are quick, simultaneous movements of both eyes in the same direction. Smooth pursuit is the ability to smoothly follow a moving object.
  • Impact: PD can cause saccadic intrusions (irregular, rapid movements) and impair smooth pursuit, leading to difficulty tracking moving objects.

b. Convergence Insufficiency:

  • Description: Difficulty focusing on close objects, leading to double vision (diplopia).
  • Impact: PD can weaken the eye muscles responsible for convergence, causing eyes to drift outward when focusing on near tasks.

Management:

  • Vision Therapy: Exercises to strengthen eye muscles and improve coordination.
  • Prism Glasses: Special lenses that can help align vision and reduce double vision.

3. Reduced Blink Rate and Dry Eyes

Causes:

  • Reduced Dopamine: Decreased dopamine levels can lead to a reduced blink rate, causing the eyes to dry out.
  • Medications: Some PD medications can contribute to dry eyes.

Impact:

  • Dry Eyes: Can cause irritation, redness, and discomfort.

Management:

  • Artificial Tears: Use of lubricating eye drops to keep the eyes moist.
  • Blinking Exercises: Conscious efforts to blink more frequently to maintain eye moisture.

4. Visual Hallucinations

Causes:

  • Medications: Dopaminergic medications can cause visual hallucinations as a side effect.
  • Disease Progression: Neurodegenerative changes in PD can affect areas of the brain involved in visual processing, leading to hallucinations.

Impact:

  • Perception of Non-Existent Objects: Patients may see shapes, people, or animals that are not present.

Management:

  • Medication Adjustments: Reducing or changing medications that may contribute to hallucinations.
  • Antipsychotic Medications: Medications like quetiapine or clozapine can help manage hallucinations.

5. Contrast Sensitivity

Description:

  • Reduced Ability to Detect Contrast: Difficulty distinguishing objects from their background, especially in low-contrast situations.

Causes:

  • Retinal Changes: PD can affect the retina, impairing contrast sensitivity.

Impact:

  • Difficulty in Low Light: Trouble seeing in dim lighting or distinguishing objects with similar colors.

Management:

  • Good Lighting: Ensuring adequate lighting in living spaces.
  • High-Contrast Objects: Using high-contrast colors for everyday items to improve visibility.

6. Visual Field Defects

Description:

  • Loss of Peripheral Vision: Reduced ability to see objects outside the central field of view.

Causes:

  • Neurodegenerative Changes: PD can affect the neural pathways involved in peripheral vision.

Impact:

  • Reduced Awareness: Difficulty noticing objects or movements to the side, increasing the risk of accidents.

Management:

  • Regular Eye Exams: Monitoring vision changes and adjusting treatments as necessary.
  • Adaptive Strategies: Training to improve awareness of peripheral vision loss and using techniques to scan the environment more effectively.

7. Color Vision

Description:

  • Impaired Color Discrimination: Difficulty distinguishing between certain colors, particularly blue and green hues.

Causes:

  • Retinal Changes: PD can cause changes in the retina that affect color perception.

Impact:

  • Difficulty with Color-Coded Information: Challenges in tasks that require color discrimination, such as reading maps or using color-coded systems.

Management:

  • Adaptive Techniques: Using other cues in addition to color for tasks, and relying on high-contrast colors.

Conclusion

Parkinson’s disease affects various aspects of vision through both motor and non-motor mechanisms. Patients may experience blurred vision, difficulty with eye movements, dry eyes, visual hallucinations, reduced contrast sensitivity, visual field defects, and impaired color vision. Comprehensive management involves regular eye exams, appropriate use of medications, vision therapy, and adaptive strategies to mitigate the impact of these visual disturbances. Collaboration between neurologists, ophthalmologists, and optometrists is crucial to providing optimal care for individuals with Parkinson’s disease.


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